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The Best Roast Beef Sandwich Recipe

This recipe makes the best roast beef sandwiches – tender, juicy roast beef is covered in creamy garlic sauce for a delicious sandwich that you will not want to put down!

The best roast beef sandwich recipe on a bun with lettuce and garlic aioli.

My favorite kind of roast beef sandwich combines soft white bread rolls and melt-in-your-mouth roast beef. This one does not disappoint!

Juicy roast beef, creamy homemade garlic aioli, and fresh lettuce come together on a toasted brioche bun to create a sandwich so good you’ll forget about everything else.

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Why You’ll Love This Recipe

This isn’t just another roast beef sandwich recipe; it’s a special treat for your taste buds! The combination of tender slices of beef, homemade garlic aioli, and buttery lettuce makes every bite pure perfection. Plus, it’s a versatile, no-fuss recipe that transforms leftover roast beef into a completely new meal.

In my opinion, a good roast beef sandwich starts with the most amazing beef roast. Use this easy sirloin tip roast beef recipe to make a roast that you can later cut into slices.

Alternately, you can go to the deli counter and ask for their best cut of meat. Have the butcher cut it into thick slices to use in this recipe. The thicker cut of meat adds to the rich flavor of this sandwich.

A roast beef sandwich on a bun with lettuce and garlic aioli.

Next, you’ll want to make a quick sauce to pair with the roast beef. We love this roasted garlic aioli recipe. It’s really what makes this sandwich so delicious and flavorful.

We have some variations and suggestions at the bottom of the post, if you don’t have time to make the sauce. But we highly recommend that you do! It’s super easy and totally worth it.

The best roast beef sandwich recipe on a bun with lettuce and garlic aioli.

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Let’s get started! Here are a few of the things that you’ll need to have in the kitchen.

Supplies

Sliced roast beef on a cutting board.

Roast Beef Sandwich Recipe

Ingredients

  • Brioche buns – Soft, fluffy, and with just the right amount of sweetness.
  • Leftover roast beef, thinly sliced – Deli roast beef works as well, but we love to use the leftovers from this mouth watering roast beef recipe. They make the best roast beef sandwiches!
  • Homemade garlic aioli – If you must, mayonnaise can be used instead of aioli.
  • Butter lettuce or green leaf lettuce – Light, crisp, and a fresh contrast to the rich beef roast.
Thin slices of roast beef to make a sandwich.

Instructions

1. Thinly slice your leftover roast beef or deli cold cuts.

Roast beef sandwich process. spreading garlic aioli on buns.

2. Open the buns and cover both sides with aioli. Place on a parchment-lined baking sheet.

Toasting buns to make roast beef sandwiches.

3. Toast the buns under a preheated oven broiler for 1-2 minutes.

A sandwich made with toasted buns, roast beef, lettuce, and garlic aioli.

4. Layer the bottom bun with roast beef, more garlic aioli, lettuce, and add the top bun.

This recipe makes 4 hot roast beef sandwiches and is the perfect way to use roast beef leftovers and create a whole new meal for the family. The leftovers can be covered in plastic wrap or put in an airtight container and refrigerated for up to three days.

The best roast beef sandwich recipe on a bun with lettuce and garlic aioli.

The beauty of this sandwich is that it’s super versatile! We, of course, love it just as it is, but you can add literally any kind of topping that you choose! Cheese sauce, blue cheese, Dijon mustard, horseradish mayo…the sky is the limit.

A sandwich recipe with toasted buns, roast beef, lettuce, and garlic aioli.

If you want to mix it up, there are a ton of delicious ways to create a leftover roast beef sandwich. I would love to see the beef sliced and layered in French bread with melted provolone cheese, like this campfire Philly cheesesteak sandwich. It’s one of our all-time favorite sandwich recipes!

Recipe Variations

  • Try making a creamy horseradish sauce or Alabama white sauce to use instead of aioli. Even our homemade BBQ sauce would be delicious!
  • Add red onion, caramelized onions, mushrooms, sauteed red peppers, or tomato slices.
  • Change it up by adding mozzarella, Swiss cheese, provolone, or even Boursin cheese.
  • Use deli meat, like sliced roast beef or prime rib, instead of a homemade roast.
  • Instead of brioche, use hoagie rolls, garlic bread, or Hawaiian rolls.
  • Try this beef dip. It’s our favorite beef crock pot recipe!
  • Have more leftovers? Make these yummy roast beef sliders.
The best roast beef sandwich recipe on a bun with lettuce and garlic aioli.

Tips and Tricks

  • Toast your buns on a low broiler setting for a warm, crispy base that won’t get soggy.
  • Use a very sharp knife for nice thin slices of roast beef. It’s the key to tender perfection.
  • Briefly warm your roast beef slices in a large skillet with a drizzle of beef broth for extra juiciness.
  • Don’t skip the aioli—it’s the secret ingredient for that amazing flavor.

Frequently Asked Questions

What’s the best cut of beef for roast beef sandwiches?
The best options are top sirloin roast, chuck roast, or eye of round roast. These cuts are tender, flavorful, and slice beautifully.

Can I use store-bought roast beef?
Absolutely! Ask for a thick cut at the deli counter for a heartier bite. Deli roast beef works like a charm when you’re short on time.

How do I store leftovers?
Wrap your assembled sandwiches tightly in plastic wrap or place the components in an airtight container. Store in the fridge for up to three days.

A roast beef sandwich on a plate with lettuce and creamy sauce, served on a glazed bun. The background includes a blurred out ingredient or condiment container. Text on the image reads: Roast Beef Sandwich Recipe and homemadeheather.com.

This recipe is a game day hero, a weeknight lifesaver, and the ultimate answer to what to do with leftover prime rib. Try it today and let the compliments roll in!

If you love this roast beef sandwich recipe, please give it a five-star review and help us share it on Facebook or Pinterest so that others can enjoy it too!

Close-up of a delectable roast beef sandwich, crafted from a classic recipe, with leafy greens and creamy sauce, served on a fresh bun. The sandwich rests on a stack of white plates with a blurred beverage can in the background.

Roast Beef Sandwich Recipe

This recipe makes the best roast beef sandwiches – tender, juicy roast beef is covered in creamy garlic sauce for a delicious sandwich that you will not want to put down!
5 from 1 vote
Prep Time: 15 minutes
Total Time: 15 minutes
Servings: 4
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Ingredients

  • 4 brioche style buns
  • 2 cups 500g leftover roast beef, thinly sliced
  • 1/2 cup homemade garlic aioli
  • Butter lettuce or green leaf lettuce

Instructions

  • Thinly slice the roast beef.
  • Open the buns and cover both sides with aioli. Place on a parchment lined baking sheet.
  • Toast the buns, open faced in the oven on low broil setting for a minute or two.
  • Layer the bottom bun with roast beef, more garlic aioli, lettuce and add the top bun.

Nutrition

Serving: 1serving | Calories: 502kcal | Carbohydrates: 38g | Protein: 10g | Fat: 35g | Saturated Fat: 11g | Polyunsaturated Fat: 23g | Cholesterol: 136mg | Sodium: 475mg | Fiber: 2g | Sugar: 7g
about heather

Hello, I’m Heather!

I'm an active mom of twin boys who is always looking for opportunities to inspire creativity through fun crafts, do-it-yourself projects and delicious recipes. This blog has been an integral part of supporting my little family and I am so grateful to have you become a part of our journey! Let's create together... Read more...

5 from 1 vote (1 rating without comment)
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You forgot to give the recipe for that aioli.