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High Protein Big Mac Pizza Recipe

Instead of going the usual pizza night pepperoni route (again), throw the family a curveball and make this Big Mac Pizza. The look on my teens’ faces when I first made this was somewhere between suspicion and joy.

A close-up of pizza slices topped with ground beef, shredded lettuce, pickles, diced onions, and an orange sauce, with a small bowl of sesame seeds in the background.

Suspicion because they weren’t sure I hadn’t lost it, and joy because, well… pizza + cheeseburgers = obviously awesome.

Let me just say, once they took a bite, there was zero doubt left. My middle teen—who claims he’s training for an “all-you-can-eat event” (not a real thing, by the way)—declared it “better than actual McDonald’s.” High praise from someone who thinks fries count as a food group.

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Why You’ll Love This Recipe

This Big Mac pizza takes everything you love about that iconic McDonald’s Big Mac—juicy beef, melty cheese, copycat Big Mac sauce, tangy pickles, and crispy lettuce—and delivers it in the best possible pizza form.

It’s easy to throw together on a weeknight, made with simple ingredients, and it’s endlessly customizable (think: low carb crusts, air fryer hacks, or even vegan swaps!).

Plus, the kids love it so much, they don’t even notice I snuck in a vegetable. Win-win!

A close-up of pizza slices topped with ground meat, shredded lettuce, pickles, onions, sesame seeds, and a creamy orange sauce on a wooden surface.

This Big Mac pizza recipe is now firmly on our regular rotation, especially on those wild weekday nights when I need an easy ground beef dinner recipe that doesn’t require begging anyone to eat a vegetable. (Spoiler: the lettuce counts.)

If you’re craving that guilty pleasure flavor but want to skip the drive-thru and do it at home—with simple ingredients you probably already have—this one’s for you.

Six bowls on a wooden surface filled with ingredients for cheeseburger salad: chopped lettuce, cooked ground beef, shredded cheddar cheese, diced onions, sliced pickles, sesame seeds, and a jar of creamy sauce.

Ingredients

Each one brings the golden arches vibes without leaving your kitchen:

  • Pizza crust – I used my high-protein turkey crust for a healthier life, but a pre-baked pizza crust or cauliflower crust works great too.
  • Lean ground beef – Browned to perfection in a large frying pan, this gives you that Big Mac hamburger flavor.
  • White onion – Diced and added for a little zing, just like the real thing.
  • Cheddar cheese – Because shredded cheddar cheese is essential for that gooey, melty bite.
  • Mozzarella cheese – Gives the pizza a creamy, stretchy finish.
  • Fresh lettuce – Shredded and added on top of the pizza after baking for a refreshing crunch.
  • Dill pickles – Thinly sliced to give every bite that tangy Big Mac toppings taste.
  • Homemade Big Mac sauce – Use store-bought burger sauce, or mix sauce ingredients at home (see tips!).
  • Sesame seeds – For that sesame seed bun finish—but on your pizza!
A rectangular, uncooked dough mixture is spread on a parchment-lined baking sheet, ready to be baked. The dough has a coarse texture and uneven edges.

Instructions

1. Start by preparing the pizza crust – follow these full instructions for my ground turkey crust.

2. In a large skillet on medium heat, brown the beef, breaking it up as it cooks. Drain excess fat and add salt and pepper if desired.

Unbaked pizza on parchment paper-lined baking sheet, topped with shredded cheese, diced onions, and crumbled cooked ground meat, ready to go in the oven.

3. Place the crust on a prepared sheet pan and layer with sauce, cheese, meat and onions.

A rectangular sheet of cheesy, baked food topped with ground beef and chopped raw onions sits on parchment paper on a baking tray. The edges are slightly browned and melted cheese is visible.

4. Bake in the oven at 350 for 10-15 minutes until the cheese is all melted.

A rectangular pizza topped with shredded lettuce, pickles, diced onions, ground meat, and a creamy sauce on parchment paper, placed on a wooden board with a pizza cutter beside it.

5. Top with Big Mac pizza toppings: iceberg lettuce, pickle slices, secret sauce and a sprinkle of sesame seeds.

A rectangular pizza topped with ground beef, melted cheese, lettuce, pickles, diced onions, and creamy sauce. A slice is being lifted from the pizza with a metal spatula.

6. Cut into slices and enjoy!

A close-up of sliced pizza topped with ground beef, melted cheese, lettuce, chopped onions, pickles, and a drizzle of sauce, placed on parchment paper on a wooden surface. A small dish of sesame seeds is nearby.

Tips & Tricks

  • Make your own sauce: Stir together mayo, ketchup, dill relish, white vinegar, onion powder, and garlic powder in a small bowl to make a killer copycat Big Mac sauce.
  • Use a pizza stone or air fryer: For that crispy crust, try baking on a pizza stone or crisping slices in the air fryer after.
  • Swap the crust: Try fathead dough, almond flour crust, or even a pillsbury crust depending on your dietary needs.
  • Cheese mix-up: Can’t find shredded cheddar? American cheese slices give it that authentic fast food twist.
  • Store it right: Leftovers keep well in an airtight container for up to 3 days. Reheat in a hot oven or skillet for best results.
A close-up of a square slice of cheeseburger pizza on a spatula, topped with ground beef, lettuce, pickles, cheese, onions, and sauce. The rest of the pizza is visible in the background.

Frequently Asked Questions

Can I make this pizza low carb or keto-friendly?
Absolutely! Use a cauliflower crust, almond flour crust, or my ground turkey crust to keep the carbs in check and turn this into a keto Big Mac pizza.

Do I bake the lettuce and pickles on the pizza?
Nope! Add those on top of the crust after baking. That way, the lettuce stays crunchy and the pickles don’t get soggy. Trust me, nobody wants a hot pickle.

Can I make this ahead of time?
Yes! You can brown ground beef ahead and store it in the fridge. Prep the crust and toppings, then assemble and bake when ready. Perfect for pizza night chaos.

A close-up of a pizza topped with shredded lettuce, sliced pickles, diced onions, sesame seeds, melted cheese, and a drizzle of creamy sauce on a wooden surface.

So next time you’re staring down a fridge full of random burger fixings and not enough buns, turn that situation into a win with this Big Mac Pizza. It’s fast, fun, and feeds a hungry crowd—which is exactly what I need when feeding teenagers who act like they’ve never seen food before.

A close-up of sliced pizza topped with ground beef, lettuce, pickles, and creamy sauce, labeled “High Protein Big Mac Pizza” with the website homemadeheather.com at the bottom.

If you love this Big Mac Pizza, please give it a 5-star rating by clicking on the stars in the recipe card below.

A close-up of pizza slices topped with ground beef, shredded lettuce, pickles, diced onions, and an orange sauce, with a small bowl of sesame seeds in the background.

High Protein Big Mac Pizza Recipe

Instead of going the usual pizza night pepperoni route (again), throw the family a curveball and make this Big Mac Pizza.
No ratings yet
Servings: 8 servings
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Ingredients

  • 1 turkey pizza crust
  • ½ pound lean ground beef
  • ¼ small white onion diced
  • 1 cup cheddar cheese shredded
  • 1 cup mozzarella cheese shredded
  • 2 cups fresh lettuce shredded
  • 1-2 dill pickles sliced
  • ¼ cup Homemade Big Mac sauce
  • 1 tsp sesame seeds

Instructions

  • Start by preparing the pizza crust according to directions on the package or make my turkey crust.
  • In a large skillet on medium heat, brown the beef, breaking it up as it cooks. Drain excess fat and add salt and pepper if desired.
  • Place the crust on a prepared sheet pan and layer with big mac sauce, cheese, meat and onions.
  • Bake in the oven at 350 for 10-15 minutes until the cheese is all melted.
  • Top with Big Mac pizza toppings: iceberg lettuce, pickle slices, secret sauce and a sprinkle of sesame seeds.
  • Cut into slices and enjoy!

Video

Notes

  • Make your own sauce: Stir together mayo, ketchup, dill relish, white vinegar, onion powder, and garlic powder in a small bowl to make a killer copycat Big Mac sauce.
  • Use a pizza stone or air fryer: For that crispy crust, try baking on a pizza stone or crisping slices in the air fryer after.
  • Swap the crust: Try fathead dough, almond flour crust, or even a pillsbury crust depending on your dietary needs.
  • Cheese mix-up: Can’t find shredded cheddar? American cheese slices give it that authentic fast food twist.
  • Store it right: Leftovers keep well in an airtight container for up to 3 days. Reheat in a hot oven or skillet for best results.

Nutrition

Serving: 1serving | Calories: 307kcal | Carbohydrates: 26g | Protein: 17g | Fat: 15g | Saturated Fat: 7g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 3g | Trans Fat: 0.1g | Cholesterol: 45mg | Sodium: 602mg | Potassium: 143mg | Fiber: 1g | Sugar: 2g | Vitamin A: 268IU | Vitamin C: 0.4mg | Calcium: 227mg | Iron: 2mg
about heather

Hello, I’m Heather!

I'm an active mom of twin boys who is always looking for opportunities to inspire creativity through fun crafts, do-it-yourself projects and delicious recipes. This blog has been an integral part of supporting my little family and I am so grateful to have you become a part of our journey! Let's create together... Read more...

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